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chenodeoxycholic acid-2,2,4,4,-d4 (cdca-d4)  (CDN Isotopes)

 
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    CDN Isotopes chenodeoxycholic acid-2,2,4,4,-d4 (cdca-d4)
    Chenodeoxycholic Acid 2,2,4,4, D4 (Cdca D4), supplied by CDN Isotopes, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/d4-chenodeoxycholic+acid+%28cdca/pm37423321-134-78-106?v=CDN+Isotopes
    Average 90 stars, based on 1 article reviews
    chenodeoxycholic acid-2,2,4,4,-d4 (cdca-d4) - by Bioz Stars, 2026-07
    90/100 stars

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    Concentration ratios of significantly differential metabolites among the three groups the pathways of lipids. *P<0.05 and FDR <0.05 for drug-15 days compared with baseline; # P<0.05 and FDR <0.05 for drug-30 days compared with baseline. FDR, false discovery rate; <t>CDCA,</t> <t>chenodeoxycholic</t> acid; UDCA, ursodeoxycholic acid.
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    Concentration ratios of significantly differential metabolites among the three groups the pathways of lipids. *P<0.05 and FDR <0.05 for drug-15 days compared with baseline; # P<0.05 and FDR <0.05 for drug-30 days compared with baseline. FDR, false discovery rate; CDCA, chenodeoxycholic acid; UDCA, ursodeoxycholic acid.

    Journal: Annals of Translational Medicine

    Article Title: Effect of roxadustat on serum metabolome and lipidome in patients with end-stage renal disease and erythropoiesis-stimulating agent resistance

    doi: 10.21037/atm-22-4451

    Figure Lengend Snippet: Concentration ratios of significantly differential metabolites among the three groups the pathways of lipids. *P<0.05 and FDR <0.05 for drug-15 days compared with baseline; # P<0.05 and FDR <0.05 for drug-30 days compared with baseline. FDR, false discovery rate; CDCA, chenodeoxycholic acid; UDCA, ursodeoxycholic acid.

    Article Snippet: Carnitine (Car) C2:0-d3, Car C10:0-d3, Car C16:0-d3, phenylalanine-d5 (Phe-d5), tryptophan-d5 (Trp-d5), cholic acid-d4 (CA-d4), and chenodeoxycholic acid-d4 (CDCA-d4) were purchased from Sigma-Aldrich and used as the internal standards (IS) for metabolomic profiling.

    Techniques: Concentration Assay

    Bile acids changes during drug treatment. (A) Concentration ratios of significantly differential bile acids among the three groups; (B) pathways of bile acids. *P<0.05 and FDR <0.05 for drug-15 days compared with baseline; # P<0.05 and FDR <0.05 for drug-30 days compared with baseline. FDR, false discovery rate; CA, cholic acid; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; GCA, glycocholic acid; GCDCA, glycochenodeoxycholic acid; GDCA, glycodeoxycholic acid; GLCA, glycolithocholic acid; GUDCA, glycoursodeoxycholic acid; LCA, lithocholic acid; TCA,taurocholic acid; TCDCA, taurochenodeoxycholicacid; TDCA, tauroursodeoxycholic acid; TLCA, taurolithocholic acid; TUDCA, tauroursodeoxycholic acid; UDCA, ursodeoxycholic acid.

    Journal: Annals of Translational Medicine

    Article Title: Effect of roxadustat on serum metabolome and lipidome in patients with end-stage renal disease and erythropoiesis-stimulating agent resistance

    doi: 10.21037/atm-22-4451

    Figure Lengend Snippet: Bile acids changes during drug treatment. (A) Concentration ratios of significantly differential bile acids among the three groups; (B) pathways of bile acids. *P<0.05 and FDR <0.05 for drug-15 days compared with baseline; # P<0.05 and FDR <0.05 for drug-30 days compared with baseline. FDR, false discovery rate; CA, cholic acid; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; GCA, glycocholic acid; GCDCA, glycochenodeoxycholic acid; GDCA, glycodeoxycholic acid; GLCA, glycolithocholic acid; GUDCA, glycoursodeoxycholic acid; LCA, lithocholic acid; TCA,taurocholic acid; TCDCA, taurochenodeoxycholicacid; TDCA, tauroursodeoxycholic acid; TLCA, taurolithocholic acid; TUDCA, tauroursodeoxycholic acid; UDCA, ursodeoxycholic acid.

    Article Snippet: Carnitine (Car) C2:0-d3, Car C10:0-d3, Car C16:0-d3, phenylalanine-d5 (Phe-d5), tryptophan-d5 (Trp-d5), cholic acid-d4 (CA-d4), and chenodeoxycholic acid-d4 (CDCA-d4) were purchased from Sigma-Aldrich and used as the internal standards (IS) for metabolomic profiling.

    Techniques: Concentration Assay